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10 Tammuz 5763 - July 10, 2003 | Mordecai Plaut, director Published Weekly
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Home and Family


PREPARING FOR THE FUTURE
Can You Just "Try It and See if it Works"?

by R' Zvi Zobin

Several arguments are often given to justify "Just trying Ritalin to see if it works" when we need to help a child who suffers from symptoms of ADD or ADHD.

ARGUMENT I:

"If someone suffers from diabetes, of course you would give him insulin," so, of course, you should give a child methylphenidate if he needs it.

This comparison is inaccurate.

Firstly, diabetes is a thoroughly researched and well understood illness caused by an inability of the pancreas to produce insulin. Treatment is to give insulin because that is the deficiency of the body. The level of sugar in the blood can be precisely tested and the effect of the insulin can be monitored accurately.

However, ADD and ADHD are not medical deficiencies of methylphenidate. The makers of Ritalin themselves state that the specific etiology of this syndrome is unknown. ADD and ADHD are only terms given to sets of symptoms and there is no single diagnostic test. Furthermore, after 50 years of clinical use, the makers of Ritalin still admit that they do not understand how it works.

A family physician once told me that when parents come to him with a request from the school to prescribe Ritalin, he prescribes vitamin tablets and tells the parents not to tell the school or the child, so they both think the child is taking Ritalin. He keeps accurate records and finds that the improvements of the child's performance are consistently as good as if he had prescribed Ritalin.

Secondly, even insulin is only prescribed to a diabetic when it is clear that the situation cannot be controlled through alternative treatment such as diet. The doctor does not say, "Let's try insulin and see if it works." If insulin is prescribed when it is not necessary, it can cause the pancreas to produce even less insulin and exacerbate the condition.

Thirdly, insulin helps all diabetics who need it, whereas methylphenidate does not help all ADD and ADHD sufferers.

ARGUMENT II:

Methylphenidate is only a very mild stimulant and is harmless.

When taken in tablet form, methylphenidate is considered to be non-addictive because it is absorbed into the blood stream slowly and it is claimed that it does not reach the brain in sufficient concentration to cause addiction. However, when absorbed directly, it has the same effect and the same potential for abuse as the major narcotics. Therefore, it is classified as a Schedule II stimulant by the FDA.

Substances in Schedule II have a high abuse potential with severe psychological or physical dependence liability, have an accepted medical use in the United States, and are available for practitioners to prescribe, dispense and administer.

Schedule II narcotics include morphine, codeine and opium. Schedule II stimulants include amphetamines (Dexedrin, Adderall, methamphetamine-Desoxyn, and methylphenidate- Ritalin). Cocaine is another Schedule II substance.

ARGUMENT III

Ritalin has been used on millions of children for many years and has been proven to be perfectly safe.

This is not correct. Stimulant medication was first used in 1937 and the drug known as Ritalin (methylphenidate) has been used since 1958. However, over forty years later, the makers of Ritalin themselves still say that the safety of methylphenidate for children less than six years has not been established and the long term effects of Ritalin in children have not been well established. They also say that drug treatment should not and need not be indefinite and usually may be discontinued after puberty.

ARGUMENT IV

It has no serious side effects. Even over-the- counter medications are packed with little notes giving long lists of possible side effects. The makers have to do that to protect themselves from the one-in-a-million chance of a serious reaction and so the list of possible side effects should not be taken seriously.

Firstly, over-the-counter medication should not be used for extended periods of time. In contrast, methylphenidate is administered for months and even years.

Secondly, a large controlled clinical study with patients using a slow-release form of methylphenidate packaged to have reduced side effects reported that the most common side effects reported were headache (14%), upper respiratory tract infection (8%), stomach ache (7%), vomiting (4%), loss of appetite (4%), sleeplessness (4%), increased cough (4%), sore throat (4%), sinusitis (3%) and dizziness (2%), which totals 54% of the patients! Other reported side effects include agitation, irritability, depression, pyschosis and a `zombie' effect causing lack of spontaneity and alertness, increased blood pressure and changes in blood constituency.

Other reactions include hypersensitivity (including skin rash, urticaria, fever, arthralgia, exfoliative dermatitis, erythema multiforme with histopathological findings of necrotizing vasculities, and thrombocytopenic purpura), anorexia; palpitations; dyskinesia; drowsiness; blood pressure and pulse changes, both up and down; tachycardia; angina; cardiac arrhythmia; abdominal pain; weight loss during prolonged therapy. There have been rare reports of Tourette's syndrome. Toxic psychosis has been reported.

A report published in theNew England Journal of Medicine stated that decreased appetite is reported in approximately 80 percent of children, but it is often mild and limited to daytime eating, and intake increases in the evening. About 10 to 15% of children have substantial weight loss. Insomnia has been reported in 3 to 85 percent, with sleep delays of about an hour. Abdominal pain, irritability, headaches, dry mouth, dizziness and depression are less frequent. Cardiovascular effects, limited to variable increases in heart rate and blood pressure, are most evident at rest and diminish with exertion.

The high incidence of these side effects indicates that we are not dealing with a `one in a million' chance of a side effect but with a medication which is far more toxic than a regular over-the-counter medication. The makers themselves and government agencies such as the FDA and NICE recommend regular blood pressure checks and periodic CBC, differential, and platelet counts during prolonged therapy.

Many of these symptoms get less with continued use, as the body adapts itself to the medication, but it is clear that the body is having to make drastic changes to adapt to a very invasive medication.

ARGUMENT V

Methylphenidate is the most proven and effective treatment for ADD and ADHD.

Studies show that administering methylphenidate is effective for 70% of ADHD sufferers. However, the same tests also showed that administering a placebo is effective for 17% of the sufferers. Reducing sugar intake is effective for 5% of the sufferers. Other studies involving giving breakfast and increasing sleep and dietary interventions all show significant effectiveness.

ADD and ADHD are terms given to sets of symptoms and are not at all diagnostic. There are many ways to deal with the symptoms.

Firstly, there are very many factors which have been proven to cause ADD and ADHD symptoms. These include insufficient sleep, allergies, food additives, vision deficiences, dehydration, fluorescent lighting, unclean air conditioner filters, heavy metals, sugar, magnesium deficiency, junk food, zinc deficiency, social stress, stress from school, Vitamin B6 deficiency, lack of stimulation from school, poor teaching and over stimulation from computer games.

For example, when one district introduced school breakfast, administrators reported that the school breakfast played a major role in the 40-50% decline in discipline issues. Researchers also noted a general increase in composite math and reading percentile scores.

Correcting the core issue automatically remediates the symptoms.

Secondly, there are many alternatives available, including exercise, coffee, herbal remedies, the Feingold diet, and high nutrition dietary additives. For example, the Australia Pediatric Journal reported that 72.7% of 55 children put on a six-week trial of the Feingold Diet demonstrated improved behavior. 26 (43.3%) remained improved following `liberalization' of the diet over a 3-6 month period.

Thirdly, many different forms of therapies, including behavioral therapy, One-Brain kinesiology and neural bio- feedback, claim proven success in alleviating symptoms.

Another aspect of resorting to only using a drug to remedy the situation is that core issues are not dealt with. The makers themselves state that careful supervision is required during drug withdrawal, since severe depression as well as the effects of chronic over-activity can be unmasked. Long- term follow-up may be required because of the patient's basic personality disturbances.

The makers themselves stress that medication should be given only after all other options have been considered and then it should be administered only as part of a general remediation program.

[Readers are invited to tell of their experiences with Ritalin, pro and con.]

 

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